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Science version about calcium and muscle contraction

Updated: Sep 18, 2023

Calcium plays a crucial role in muscle contraction. When a nerve impulse reaches the muscle, it triggers the release of acetylcholine, which initiates an action potential. This action potential travels along the muscle cell membrane and causes the release of calcium ions from the sarcoplasmic reticulum, a storage site for calcium within the muscle cell.

The released calcium binds to troponin, a protein in the thin filament of the muscle. This binding causes a conformational change that exposes the myosin-binding sites on actin. With the myosin-binding sites exposed, the myosin heads on the thick filament bind to actin, forming cross-bridges.

The myosin heads undergo a power stroke, pulling the actin filaments toward the center of the sarcomere, resulting in muscle contraction. ATP provides the energy for this process. After muscle contraction, the calcium is actively pumped back into the sarcoplasmic reticulum, which allows the troponin to revert to its original conformation, covering the myosin-binding sites on actin and preventing further cross-bridge formation. Adequate dietary calcium is crucial to ensure sufficient calcium availability for muscle contraction.

However, when there is an insufficient intake of dietary calcium, the body may withdraw calcium from the bones to meet the immediate calcium needs for muscle contraction and other essential functions. This process, known as bone resorption, involves the release of calcium from the bones into the bloodstream, where it can be transported to various tissues, including the muscles.


To support muscle contraction and maintain bone health, it's important to ensure an adequate intake of dietary calcium. Good dietary sources of calcium include dairy products (milk, cheese, yogurt), leafy green vegetables (kale, spinach), fortified plant-based milk alternatives, tofu, and canned fish with bones (such as sardines). If necessary, calcium supplements can also be considered, but it's advisable to consult with an accredited dietitian for personalized guidance on calcium intake and supplementation based on your specific needs.



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